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化浪百科

卡非佐米

英文名稱:Carfilzomib

卡非佐脒; 卡菲佐米

英文別稱:UNII-72X6E3J5AR; Carfilzomib (PR-171)

CAS : 868540-17-4 精確質量 : 719.42600
分子式 : C40H57N5O7 logP : 4.08500
分子量 : 719.91000 PSA : 158.47000
化浪參考價: ¥7338.00

化合物簡介

Carfilzomib (marketed under the trade name Kyprolis, developed by Onyx Pharmaceuticals) is an anti-cancer drug acting as a selective proteasome inhibitor. Chemically, it is a tetrapeptide epoxyketone and an analog of epoxomicin.
The U.S. Food and Drug Administration (FDA) approved it on 20 July 2012 for use in patients with multiple myeloma who have received at least two prior therapies, including treatment with bortezomib and an immunomodulatory therapy (such as lenalidomide) and have demonstrated disease progression on or within 60 days of completion of the last therapy. Approval is based on response rate. Clinical benefit, such as improvement in survival or symptoms, has not been verified.
The abbreviation CFZ is common for referring to carfilzomib, but abbreviating drug names is not best practice in medicine.

物化性質

密度:1.162g/cm3

沸點:975.627ºC at 760 mmHg

閃點:543.84ºC

折射率:1.551

安全信息

海關編碼:2933790090

合成路線

毒性

暫無

圖譜

暫無

MSDS

暫無

上下游產品

上游產品 總計: 11查看更多
下游產品 總計: 11查看更多

海關數據

國家名稱 海關編碼 海關數據更新時間
中國 2933790090 2019-03
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